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Schircks Laboratories LOGO.jpg


艾美捷科技代理Schircks Laboratories品牌。

瑞士Schircks Laboratories由B.Schircks博士于1980年创立，主要生产蝶啶及蝶啶类化合物（Pteridines）。至今，Schircks实验室合成了100多种蝶啶类化合物，主要用于科学研究和临床诊断应用。产品包括：

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11.1806-(L-1,2,3-Trihydroxybutyl)-pterin [Rhamnopterin]
11.182(6R,S)-5,6,7,8-Tetrahydro-L-rhamnopterin dihydrochloride
11.203L-Biopterin [L-erythro-Biopterin] 
11.2067,8-Dihydro-L-biopterin
11.209(6R,S)-5,6,7,8-Tetrahydro-L-biopterin dihydrochloride 
11.212(6R)-5,6,7,8-Tetrahydro-L-biopterin dihydrochloride
11.213(6R)-5,6,7,8-Tetrahydro-L-biopterin dihydrochloride
11.215(6S)-5,6,7,8-Tetrahydro-L-biopterin sulfate
11.216(6S)-5,6,7,8-Tetrahydro-L-biopterin sulfate
11.217(6R)-5-Methyl-5,6,7,8-tetrahydro-L-biopterin dihydrochloride
11.218D-Biopterin [D-erythro-Biopterin]
11.220(6R,S)-5,6,7,8-Tetrahydro-D-biopterin dihydrochloride
11.221D-threo-Biopterin [Dictyopterin] 
11.223(6R,S)-5,6,7,8-Tetrahydro-D-threo-biopterin dihydrochloride 
11.228Deoxysepiapterin
11.2296-((1R,S)-Hydroxypropyl)pterin [(1'R,S)-2'-Deoxybiopterin]
11.2317-Biopterin 
11.2347-Tetrahydro-L-biopterin dihydrochloride
11.260Oncopterin
11.2704-Hydroxy-6-(L-erythro-1,2-dihydroxy-propyl)-2-(methylthio)pteridine
11.2804-Amino-L-biopterin [2,4-Diamino-6-(L-erythro-1',2'-dihydroxypropyl)pteridine]
11.2824-Amino-(6R,S)-5,6,7,8-tetrahydro-L-biopterin dihydrochloride
11.2834-Amino-(6R)-5,6,7,8-tetrahydro-L-biopterin dihydrochloride
11.303D-Neopterin [D-erythro-Neopterin] 
11.3067,8-Dihydro-D-neopterin  
11.3077,8-Dihydro-D-neopterin-3’-triphosphate  (Please refer to our reference 8)
11.309(6R,S)-5,6,7,8-Tetrahydro-D-neopterin dihydrochloride
11.314D-Neopterin-3’-monophosphate, lithium salt
11.3157,8-Dihydro-D-neopterin-3’-monophosphate, lithium salt  
11.3203'-Hydroxy-D-sepiapterin
11.3307-Neopterin  
11.340L-Monapterin [L-threo-Neopterin]
11.3457,8-Dihydro-L-monapterin
11.346(6R,S)-5,6,7,8-Tetrahydro-L-monapterin dihydrochloride
11.349D-Monapterin [D-threo-Neopterin]
11.403Pterin-6-carboxylic acid
11.409Pterin-7-carboxylic acid
11.4156-Formylpterin [Pterin-6-aldehyde]
11.4166-Formyl-7,8-dihydropterin
11.418Acetyl-6-formylpterin
11.4206-Hydroxymethylpterin
11.4216-Hydroxymethyl-7,8-dihydropterin hydrochloride
11.4226-Hydroxymethyl-7,8-dihydropterin-diphosphate    (Please refer to our reference 8)
11.423(6R,S)-6-Hydroxymethyl-5,6,7,8-tetrahydropterin dihydrochloride
11.4296-Hydroxymethylpterin-monophosphate 
11.4386-Hydroxymethylpterin-diphosphate, lithium salt  
11.4806-Methylpterin
11.4816-Methyl-7,8-dihydropterin hydrochloride
11.483(6R,S)-6-Methyl-5,6,7,8-tetrahydropterin dihydrochloride
11.5036,7-Dimethylpterin
11.5066,7-Dimethyl-7,8-dihydropterin monohydrochloride
11.5096,7-Dimethyl-5,6,7,8-tetrahydropterin monohydrochloride
11.703Leucopterin
11.713Xanthopterin
11.716Dihydroxanthopterin
11.723Isoxanthopterin
11.903Pterin
11.9067,8-Dihydropterin  (Please refer to our reference 20)
11.9095,6,7,8-Tetrahydropterin dihydrochloride
13.103Lumazine
13.2036-Hydroxylumazine
13.2066-Hydroxy-7,8-dihydrolumazine
13.2207-Hydroxylumazine
16.113Pteroic acid
16.123N10-(Trifluoroacetyl)pteroic acid
16.14010-Formylpteroic acid
16.203Folic acid  
16.2067,8-Dihydrofolic acid
16.208(6S)-5,6,7,8-Tetrahydrofolic acid trihydrochloride  
16.209(6R,S)-5,6,7,8-Tetrahydrofolic acid trihydrochloride 
16.21110-Methylfolic acid
16.21510-Formylfolic acid  
16.21710-Formyl-5,6,7,8-tetrahydrofolic acid  (Please refer to our reference 19)
16.220(6R,S)-5-Formyl-5,6,7,8-tetrahydrofolic acid, calcium salt 
16.222(6R)-5-Formyl-5,6,7,8-tetrahydrofolic acid, calcium salt (unnatural calcium folinate)  
16.230(6R,S)-5,10-Methenyl-5,6,7,8-tetrahydrofolic acid chloride
16.233(6R,S)-5-Methyl-5,6-dihydrofolic acid, ammonium salt  
16.235(6R,S)-5-Methyl-5,6,7,8-tetrahydrofolic acid, calcium salt
16.236(6S)-5-Methyl-5,6,7,8-tetrahydrofolic acid, calcium salt
16.243(6R,S)-5-Methyl-5,6,7,8-tetrahydropteroyltri-γ-L-glutamic acid trihydrochloride
16.244(6R,S)-5-Methyl-5,6,7,8-tetrahydropteroyltetra-γ-L-glutamic acid trihydrochloride
16.252Pteroyldi-γ-L-glutamic acid  
16.253Pteroyltri-γ-L-glutamic acid   has been discontinued
16.254Pteroyltetra-γ-L-glutamic acid  
16.255Pteroylpenta-γ-L-glutamic acid  has been discontinued
16.266Pteroylhexa-γ-L-glutamic acid, ammonium salt
16.267Pteroylhepta-γ-L-glutamic acid, ammonium salt  
16.280(6R,S)-5-Formyl-5,6,7,8-tetrahydropteroic acid
16.282(6R,S)-5-Formyl-5,6,7,8-tetrahydropteroyldi-γ-L-glutamic acid, lithium salt has been discontinued
16.283(6R,S)-5-Formyl-5,6,7,8-tetrahydropteroyltri-γ-L-glutamic acid, lithium salt has been discontinued
16.284(6R,S)-5-Formyl-5,6,7,8-tetrahydropteroyltetra-γ-L-glutamic acid, lithium salt
16.285(6R,S)-5-Formyl-5,6,7,8-tetrahydropteroylpenta-γ-L-glutamic acid, lithium salt
16.286(6R,S)-5-Formyl-5,6,7,8-tetrahydropteroylhexa-γ-L-glutamic acid, lithium salt
16.330Aminopterin [4-Aminofolic acid]
16.4034-Amino-10-methylpteroic acid (APA, DAMPA)
16.411Methotrexate  [4-Amino-10-methylpteroyl-γ-L-glutamic acid]
16.4124-Amino-10-methylpteroyldi-γ-L-glutamic acid, ammonium salt [Methotrexate diglutamate]
16.4134-Amino-10-methylpteroyltri-γ-L-glutamic acid, ammonium salt [Methotrexate triglutamate] 
16.4144-Amino-10-methylpteroyltetra-γ-L-glutamic acid, ammonium salt [Methotrexate tetraglutamate] 
16.4154-Amino-10-methylpteroylpenta-γ-L-glutamic acid, ammonium salt [Methotrexate pentaglutamate]
16.4164-Amino-10-methylpteroylhexa-γ-L-glutamic acid, ammonium salt [Methotrexate hexaglutamate]
16.4174-Amino-10-methylpteroylhepta-γ-L-glutamic acid, ammonium salt [Methotrexate heptaglutamate] 
16.5007-Hydroxymethotrexate   
16.701p-Aminobenzoyl-L-glutamic acid
16.702p-Aminobenzoyldi-γ-L-glutamic acid, ammonium salt  
16.703p-Aminobenzoyltri-γ-L-glutamic acid, ammonium salt  
16.704p-Aminobenzoyltetra-γ-L-glutamic acid, ammonium salt  
16.705p-Aminobenzoylpenta-γ-L-glutamic acid, ammonium salt  
16.706p-Aminobenzoylhexa-γ-L-glutamic acid,  ammonium salt 
16.707p-Aminobenzoylhepta-γ-L-glutamic acid, ammonium salt  has been discontinued
16.901Z-Glu-OtBu
16.902Z-Glu2-OtBu3
16.903Z-Glu3-OtBu4  
16.904Z-Glu4-OtBu5  
16.905Z-Glu5-OtBu6  
16.906Z-Glu6-OtBu7  
91.303D-(5-15N)-Neopterin
96.203(5-15N)-Folic acid 
< " data-original="http://bio-helix.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="艾美捷科技代理Schircks Laboratories品牌"> 艾美捷科技代理Schircks Laboratories品牌
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invivoCrown IV0107替换BioXCell BE0273 invivoCrown IV0107替换BioXCell BE0273
InVivoPro Anti-Mouse PD-1(CD279) in vivo antibody, Clone 29F.1A12 ...
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invivoCrown IV0108替换BioXCell BE0034 invivoCrown IV0108替换BioXCell BE0034
InVivoPro Anti-Mouse LPAM-1 (Integrin α4β7) in vivo antibody, Clone DATK32 ...
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AllerMAbs.jpg

艾乐美生物科技有限公司（AllerMAbs Co., Ltd.）成立于2015年，是台湾一家专注于生产高亲和力、高纯度并具有过敏原特异性的嵌合人类IgE单克隆抗体的生物公司。公司创办人团队在科研过程中发现市面上缺乏多样的IgE单克隆抗体，特別是具有过敏原特异性的人IgE 单抗。如果能制备出这种抗体，将有助于IgE 相关领域的研究工作。因此，AllerMAbs公司团队开始思考与研究利用基因克隆动物来制造人类 IgE 抗体的可行性，经过数年的努力于 2014年开发出人类IgE 抗体基因嵌入小鼠，通过杂交瘤技术 (Hybridoma technology)，成功地研制出分泌嵌合人类IgE 单抗的 IgE 杂交瘤与纯化 IgE 抗体。经测试，此种嵌合人类IgE 单抗的物化性质与对免疫细胞的活性，皆与人类IgE 抗体一致，研究成果于2015 年发表在国际学术期刊上。

 

AllerMAbs的产品解决了目前人类IgE抗体不易制备的问题，让嵌合人类IgE抗体可以成为人类IgE抗体的替代品，并提供一个更稳定、更符合血清IgE检测系统的校正品，让临床血清IgE的检测结果更加准确与可靠。

 

其利用动物基因转殖技术，将组成人类IgE抗体分子的ε重链(Heavy chain)和κ轻链(Light chain)的编码基因(Encoding genes)，分別嵌入(Knock-in)小鼠胚胎干细胞(Embryonic stem cells, ES cells)的γ1重链和κ轻链基因的位置，接着把胚胎干细胞分別植入孕母鼠体内，并将其带有嵌入基因之成鼠交互配种，最后得到带有人类IgE抗体重链和轻链基因的基因嵌入小鼠(HεκKI mice)，且体内能制造完整的嵌合人类IgE抗体分子。

 

技术优势

容易制备IgE杂交瘤与IgE单抗

过敏原特异性

良好的亲和力与专一性

高纯度与高稳定性

可结合至嗜碱性粒细胞上的IgE受体与刺激細胞

可大量生产与高浓度制备

非人类血液来源(相较于血清IgE抗体)

适合用作检测用的校正品

" data-original="http://bio-helix.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="AllerMAbs"> AllerMAbs
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invivoCrown IV0101替换BioXCell BE0101 invivoCrown IV0101替换BioXCell BE0101
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invivoCrown IV0101替换BioXCell BE0101 invivoCrown IV0101替换BioXCell BE0101
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Calbiotech.jpg

Calbiotech是为世界各地的大学和研究中心定制开发和制造免疫产品的主要参考实验室，产品包括ELISA、超灵敏的化学发光试剂，IVD RIA和PCR试剂盒。

 

Calbiotech specializes in immunoassay development and manufacturing, with a comprehensive range of ELISA and CLIA assays for human and animal research, including specific assays for hormone, autoimmune disorders, cancer, infectious diseases and much more. The company has over 200 products which are distributed to over 80 countries globally.

 

Calbiotech is a key partner for biotech, pharma and CROs, providing contract manufacturing and assay development services, including custom coated microplates, reagents, buffers and other assay components.

 

Calbiotech的主要产品包括：

（1）ELISA KITS

Products For Research

Products For Export

（2）DEVELOPMENT REAGENTS

Coated Plates

Coating & Blocking Buffers

Stabilizers & Substrates

Sample Prep & Assay Optimization

Commons: Wash, Stop, TMB, PBS

（3）CHEMILUMINESCENT

SAV Coated Magnetic Beads

Chemiluminescent Immunoassays

" data-original="http://bio-helix.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="Calbiotech"> Calbiotech
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invivoCrown IV0101替换BioXCell BE0101 invivoCrown IV0101替换BioXCell BE0101
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